Background Osteoporosis is a common metabolic bone disease. We conducted a multi-center, double- placebo, double-blind study to verify the effects of calcium aspartate anhydrous on osteoporosis. Methods 1,306 patients with an initial t-score of –1.5 or lower were randomly assigned to receive calcium aspartate anhydrous (CalAA, 520mg elemental per day) and a placebo, or calcium citrate (1500 mg elemental per day) and vitamin D (1000 IU per day), or two placebos. Results At 3 months, the bone mineral density (BMD) at the lumbar spine had increased by a mean of 4.07% in the CalAA group, 0.64 percent in the calcium citrate group and there was no significant change in the double-placebo group. The BMD of the total hip had increased by a mean of 3.37 percent in the CalAA group. No significant change was detected in the calcium citrate group or the double-placebo group. At 12 months, lumbar spine BMD had increased by a mean of 5.66 percent in the CalAA group, while the calcium citrate group and the double-placebo group saw decline of 0.51% and 0.75% respectively. Total hip BMD had increased by a mean of 4.11 percent in the CalAA group while there was no significant change in the calcium citrate group. Total hip BMD declined by a mean of 1.17% in the double-placebo group.
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Showing posts with label Osteroporosis. Show all posts
Showing posts with label Osteroporosis. Show all posts
Thursday, November 15, 2007
Medications For Prevention And Treatment Of Osteoporosis
Medications for Prevention and Treatment of Osteoporosis. steoporosis is a disease where the strength of bones is less than normal, making them more susceptible to fracture, or breaking, than normal bones. Any bone will break if subjected to enough force, but a bone with osteoporosis may break with very little trauma, or sometimes with no trauma at all. Fractures can cause pain, loss of independence, and shorten your life. The best time to detect osteoporosis is before a fracture happens, and the best way to do that is with a bone density test. The “gold-standard” method of measuring bone density is by DXA (Dual-energy X-ray Absorptiometry) of the spine and hip. If the “T-score” on the DXA test is less than or equal to –2.5, then a diagnosis of osteoporosis may be made. If you have osteoporosis, or low bone density, there are medications that can strengthen your bones and reduce the future risk of fractures. Medications can help whether or not you have already had a fracture, whether you are male or female, and even if you are very old. Since there are many medications for osteoporosis, it is important that you have a good understanding of the risks and benefits with each of them. The more you know, the better you are able to select the one that is best for you.
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Friday, November 9, 2007
Bone Health And Osteoporosis: A Report Of The Surgeon General
By United States Public Health Service Surgeon General of the United States
This first-ever Surgeon General’s Report on bone health and osteoporosis illustrates the large burden that bone disease places on our Nation and its citizens. Like other chronic diseases that disproportionately affect the elderly, the prevalence of bone disease and fractures is projected to increase markedly as the population ages. If these predictions come true, bone disease and fractures will have a tremendous negative impact on the future well-being of Americans. But as this report makes clear, they need not come true: by working together we can change the picture of aging in America. Osteoporosis, fractures, and other chronic diseases no longer should be thought of as an inevitable part of growing old. By focusing on prevention and lifestyle changes, including physical activity and nutrition, as well as early diagnosis and appropriate treatment, Americans can avoid much of the damaging impact of bone disease and other chronic diseases.
This Surgeon General’s Report brings together for the first time the scientific evidence related to the prevention, assessment, diagnosis, and treatment of bone disease. More importantly, it provides a framework for moving forward. The report will be another effective tool in educating Americans about how they can promote bone health throughout their lives.
This first-ever Surgeon General’s Report on bone health and osteoporosis provides much needed information on bone health, an often overlooked aspect of physical health. This report follows in the tradition of previous Surgeon Generals’ reports by identifying the relevant scientific data, rigorously evaluating and summarizing the evidence, and determining conclusions.
Read Online (PDF)
This first-ever Surgeon General’s Report on bone health and osteoporosis illustrates the large burden that bone disease places on our Nation and its citizens. Like other chronic diseases that disproportionately affect the elderly, the prevalence of bone disease and fractures is projected to increase markedly as the population ages. If these predictions come true, bone disease and fractures will have a tremendous negative impact on the future well-being of Americans. But as this report makes clear, they need not come true: by working together we can change the picture of aging in America. Osteoporosis, fractures, and other chronic diseases no longer should be thought of as an inevitable part of growing old. By focusing on prevention and lifestyle changes, including physical activity and nutrition, as well as early diagnosis and appropriate treatment, Americans can avoid much of the damaging impact of bone disease and other chronic diseases.
This Surgeon General’s Report brings together for the first time the scientific evidence related to the prevention, assessment, diagnosis, and treatment of bone disease. More importantly, it provides a framework for moving forward. The report will be another effective tool in educating Americans about how they can promote bone health throughout their lives.
This first-ever Surgeon General’s Report on bone health and osteoporosis provides much needed information on bone health, an often overlooked aspect of physical health. This report follows in the tradition of previous Surgeon Generals’ reports by identifying the relevant scientific data, rigorously evaluating and summarizing the evidence, and determining conclusions.
Read Online (PDF)
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